Retin-A

Active Ingredients:

• Tretionon

How does Retin-A work and what pharmaceutical group does it belong to?

The preparation belongs to a group of drugs used in acne treatment. Tretinoin expresses a wide variety of effects when applied to skin. The preparation induces transcription in the epithelium cells, promotes epithelium renewal, decreases cellular adhesion in cells that form comedones, prevents the formation of keratic plugs. The preparation should be used in cases of I-II degree acne however in severe cases it should be used as subsidiary therapy alongside antibiotics. The preparation also prevents the formation of comedones.

Which conditions are treated with Tretinoin?

The preparation is indicated in treatment of:

• Acne vulgaris
• Follicular keratosis
• Flat wart
• Hyperpigmentation

What should a patient know before using Retin-A?

The Tretinoin should not be used in cases of:

• Hypersensitivity to any components of the preparation
• Pregnancy
• Lactation period
• Age prior to 12 years

The preparation should be used with caution in:

• Seborrheal dermatitis
• Excema
• Sunburns
• Liver failure
• Pancreatitis
• Chronic renal failure
• Chronic intoxication
• Diabetes

Which adverse effects may manifest when using the medication?

The side effects of Retin-A include:

• Local reactions: allergic reactions, hypopigmentation, hyperemia, skin hyperpigmentation.

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Tretinoin?

The drug is affected by the following:

• Locally used preparations
• Drugs that may cause photosensibilization
• Other retionids
• Viatmins

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Retin-A is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.